Causes of Hepatitis C


Hepatitis C infection occurs due to the hepatitis C virus or HCV. The virus spreads when there is contact with infected blood. The causes of Hepatitis C or rather the main modes of transmission of the virus are as follows:

  • Since blood screening tests were not up to the mark prior to 1992, it was possible for the hepatitis C virus to spread through blood transfusions and organ transplants. Now with significant improvements in these tests, detection of the virus is possible.
  • The hepatitis C virus can spread through shared contaminated needles during illicit drug use.
  • In some cases, babies may become infected with the virus during childbirth if their mothers have the infection.
  • In rare cases, the hepatitis C virus can spread through sexual relations.
The risk of Hepatitis C increases in the following groups of people:

  • Those with HIV
  • Health care workers who come in contact with infected blood
  • Those who inject drugs
  • Those who have had body piercings or tattoos in unhygienic environments
  • Those who have undergone blood transfusions or organ transplants prior to 1992
  • Those who have received clotting factor concentrates prior to 1987.
  • Those who have undergone hemodialysis treatment for a long course of time
  • Individuals born to mothers with hepatitis C infection
The hepatitis C infection can persist over a number of years and can lead to the following complications:

  • Cirrhosis: Cirrhosis or scarring of the liver tissue usually develops about 20 to 30 years after the infection. When cirrhosis occurs, liver functioning may be affected.
  • Liver Cancer: Liver cancer may occur in some individuals with hepatitis C infection.
  • Liver Failure: Hepatitis C infection may cause severe damage to the liver and hamper normal liver functioning.

References
  1. Alajos Pár, László Telegdy, Lajos Dalmi, Eva Müller, Hungarian Viral Hepatitis Treatment Study Group, Therapy for chronic hepatitis C, Journal of Physiology-Paris, Volume 95, Issues 1–6, January–December 2001, Pages 399-405, ISSN 0928-4257, 10.1016/S0928-4257(01)00054-7.
  2. Jacqueline Rhoads, Natural History and Epidemiology of Hepatitis C, Journal of the Association of Nurses in AIDS care, Volume 14, Issue 5, Supplement, September–October 2003, Pages 18S-25S, ISSN 1055-3290, 10.1177/1055329003254854.
  3. Samer S. El-Kamary, Michelle D. Shardell, Mohamed Abdel-Hamid, Soheir Ismail, Mohamed El-Ateek, Mohamed Metwally, Nabiel Mikhail, Mohamed Hashem, Amr Mousa, Amr Aboul-Fotouh, Mohamed El-Kassas, Gamal Esmat, G. Thomas Strickland, A randomized controlled trial to assess the safety and efficacy of silymarin on symptoms, signs and biomarkers of acute hepatitis, Phytomedicine, Volume 16, Issue 5, May 2009, Pages 391-400, ISSN 0944-7113, 10.1016/j.phymed.2009.02.002.